After 11 years of research, scientists unlock a new weakness in deadly fungi

Fungal infections are becoming deadlier as drug resistance spreads and treatment options stall. Researchers at McMaster University discovered that a molecule called butyrolactol A can dramatically weaken dangerous fungi, allowing existing antifungal drugs to work again. Instead of killing the fungus directly, the molecule sabotages a vital internal system, leaving the pathogen exposed. The breakthrough could help revive an entire class of antifungal medicines once thought obsolete.